What does all the bad press on heartburn medications (PPI) really mean?
From the Doctor’s Blog June 8, 2016
A recent article in JAMA (Journal of the American Medical Association) Neurology, examined insurance claims of over 73,000 people ages 75 and older, who were free of dementia at the start of the study. Over a period of 7 years, those who took PPI’s (Nexium, Prilosec, etc.) had a 44% increased probability of being diagnosed with dementia. The author notes that the PPI’s may not have directly caused dementia, as older people take many drugs (polypharmacy) and that is a risk factor for dementia in and of itself.
Another study published in January in JAMA (Journal of the American Medical Association) Internal Medicine associated use of PPI’s with increased risk of chronic kidney disease (CKD). The authors suggest these widely used drugs might be part of the reason CKD prevalence has risen faster than to be expected knowing the trends for usual risk factors of CKD, such as diabetes and hypertension (high blood pressure).
Helpful Lifestyle Changes for Reducing Heartburn Symptoms:
- Lose weight if needed
- Stop smoking
- Limit alcohol and carbonated beverages
- Avoid foods that can trigger heartburn, such as fatty or acidic foods
- Eat smaller meals
- Do not eat close to bedtime
- Remaining upright after meals
- Wear loose-fitting clothes